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SW19 CPFC Addiscombe West 23 Nov 20 1.59pm | |
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Originally posted by Eaglecoops
Those brought up in the thalidomide era will have an inbuilt nervousness to vaccines given that was a drug that had already been declared safe. The vaccines currently being developed are a new technology that is in its infancy. If you want to go shooting that up straight away then more power to you but I’m going to hang on for a bit and I don’t need someone telling me that I should be following the science. After all they were the ones who said masks are useless and changed their mind to really important. I hope it’s not those scientists that are working on the vaccine in case they go, “it’s totally safe “ followed by “Doh!” This isn’t strictly true. The Oxford vaccine does not use mRNA, and uses a more traditional approach - having read up on it this is likely to be the safest bet as mRNA vaccines have not been approved anywhere in the world until now. There is potentially a chance of auto immune side effects that will only come out in long term studies once this has been administered. The good news is the Oxford version is cheaper, can be stored in a normal fridge and the UK govt probably favours that for the NHS over the mRNA versions. I will be getting one but would prefer the Oxford version. If that is not available I’ll try to obtain it privately. Not keen on the mRNA concept until longer term results have been gathered and peer reviewed.
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SW19 CPFC Addiscombe West 23 Nov 20 2.06pm | |
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Also, this mass testing approach is mind boggling. Everywhere on the media, a lot of positivity about it being a strategy to avoid lockdowns or even reduce cases, which on the surface of it sounds sensible. But the issue that no one appears to be focusing on is the fact that the type of tests used are at best 65% accurate. SIXTY FIVE. That is mental. Borderline useless. PCR tests are the only option worth considering, and even they are only 70-90% accurate. This is being mentioned but not highlighted by a lot of reports. There is no way I’d ever consider taking a rapid test with such low accuracy. Why? Because there’s a good chance I get a false positive and then I’m off work for 2 weeks for no reason. Or, I get a false negative, which is even worse. I’d rather isolate for 48 hours and rely on a PCR, personally. Edited by SW19 CPFC (23 Nov 2020 2.06pm)
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Stirlingsays 23 Nov 20 2.16pm | |
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Originally posted by SW19 CPFC
Also, this mass testing approach is mind boggling. Everywhere on the media, a lot of positivity about it being a strategy to avoid lockdowns or even reduce cases, which on the surface of it sounds sensible. But the issue that no one appears to be focusing on is the fact that the type of tests used are at best 65% accurate. SIXTY FIVE. That is mental. Borderline useless. PCR tests are the only option worth considering, and even they are only 70-90% accurate. This is being mentioned but not highlighted by a lot of reports. There is no way I’d ever consider taking a rapid test with such low accuracy. Why? Because there’s a good chance I get a false positive and then I’m off work for 2 weeks for no reason. Or, I get a false negative, which is even worse. I’d rather isolate for 48 hours and rely on a PCR, personally. Edited by SW19 CPFC (23 Nov 2020 2.06pm) Gives pause as to why the accuracy is that low. Perhaps even with the number of people working on these technologies given the time and complexity it just isn't enough to produce the kind of reliability for real credibility. We know this virus is a sars variant so it's not like it's out of the blue....but then again, there was no vaccine for Sars in 2008 and at least they are producing them now. Edited by Stirlingsays (23 Nov 2020 2.16pm)
'Who are you and how did you get in here? I'm a locksmith. And, I'm a locksmith.' (Leslie Nielsen) |
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Eaglecoops CR3 23 Nov 20 2.37pm | |
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Originally posted by SW19 CPFC
This isn’t strictly true. The Oxford vaccine does not use mRNA, and uses a more traditional approach - having read up on it this is likely to be the safest bet as mRNA vaccines have not been approved anywhere in the world until now. There is potentially a chance of auto immune side effects that will only come out in long term studies once this has been administered. The good news is the Oxford version is cheaper, can be stored in a normal fridge and the UK govt probably favours that for the NHS over the mRNA versions. I will be getting one but would prefer the Oxford version. If that is not available I’ll try to obtain it privately. Not keen on the mRNA concept until longer term results have been gathered and peer reviewed. Is the mRNA the one they have ordered only 5 million doses of or was that the other one?
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Willo South coast - west of Brighton. 23 Nov 20 2.40pm | |
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Originally posted by Eaglecoops
Is the mRNA the one they have ordered only 5 million doses of or was that the other one? This is the American 'Moderna' vaccine which I understand works on the RNA principle, in fact the last three letters of 'Moderna' is RNA ! Edited by Willo (23 Nov 2020 2.41pm)
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Wisbech Eagle Truro Cornwall 23 Nov 20 3.12pm | |
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Originally posted by SW19 CPFC
Also, this mass testing approach is mind boggling. Everywhere on the media, a lot of positivity about it being a strategy to avoid lockdowns or even reduce cases, which on the surface of it sounds sensible. But the issue that no one appears to be focusing on is the fact that the type of tests used are at best 65% accurate. SIXTY FIVE. That is mental. Borderline useless. PCR tests are the only option worth considering, and even they are only 70-90% accurate. This is being mentioned but not highlighted by a lot of reports. There is no way I’d ever consider taking a rapid test with such low accuracy. Why? Because there’s a good chance I get a false positive and then I’m off work for 2 weeks for no reason. Or, I get a false negative, which is even worse. I’d rather isolate for 48 hours and rely on a PCR, personally. Edited by SW19 CPFC (23 Nov 2020 2.06pm) I heard a piece on Radio 4 very early today in which an expert, whose name escaped me, explained that we need to stop comparing the tests. I'll do my best to explain what I think was said. Apparently the fast test measures not whether you are infected but whether you are infectious. The PCR test takes longer and detects smaller vaccine loads, even after you stop being infections. The fast test will identity those, even those without symptoms, who can infect others with a heavier current viral load. So although not highly reliable it must be thought of as a tool to be used as an alternative to isolation rather than an alternative to the PCR test. False positives will be revealed by a PCR test.
For the avoidance of doubt any comments in response to a previous post are directed to its ideas and not at any, or all, posters personally. |
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BlueJay UK 23 Nov 20 3.16pm | |
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Originally posted by Eden Eagle
Article from Nature Communications casting doubt on asymptomatic transmission- “there were no positive tests among 1,174 close contacts of asymptomatic cases”. Interesting if true! If this can or has been replicated outside of China it's useful to know.
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cryrst The garden of England 23 Nov 20 3.20pm | |
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Originally posted by SW19 CPFC
Also, this mass testing approach is mind boggling. Everywhere on the media, a lot of positivity about it being a strategy to avoid lockdowns or even reduce cases, which on the surface of it sounds sensible. But the issue that no one appears to be focusing on is the fact that the type of tests used are at best 65% accurate. SIXTY FIVE. That is mental. Borderline useless. PCR tests are the only option worth considering, and even they are only 70-90% accurate. This is being mentioned but not highlighted by a lot of reports. There is no way I’d ever consider taking a rapid test with such low accuracy. Why? Because there’s a good chance I get a false positive and then I’m off work for 2 weeks for no reason. Or, I get a false negative, which is even worse. I’d rather isolate for 48 hours and rely on a PCR, personally. Edited by SW19 CPFC (23 Nov 2020 2.06pm) I think self tests may be the giving the false pos and negs.
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BlueJay UK 23 Nov 20 3.21pm | |
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Originally posted by Badger11
I suspect that providing proof to the destination country that you have been vaccinated will become standard for people who wish to travel abroad. The anti vaxers may find themselves stuck at home. As it should be. And as they should be. If you're travelling to some countries you already need certain vaccinations. Nothing new. Edited by BlueJay (23 Nov 2020 3.25pm)
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SW19 CPFC Addiscombe West 23 Nov 20 3.22pm | |
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Originally posted by Wisbech Eagle
I heard a piece on Radio 4 very early today in which an expert, whose name escaped me, explained that we need to stop comparing the tests. I'll do my best to explain what I think was said. Apparently the fast test measures not whether you are infected but whether you are infectious. The PCR test takes longer and detects smaller vaccine loads, even after you stop being infections. The fast test will identity those, even those without symptoms, who can infect others with a heavier current viral load. So although not highly reliable it must be thought of as a tool to be used as an alternative to isolation rather than an alternative to the PCR test. False positives will be revealed by a PCR test. No one is saying false positives or negatives will not be issued by a PCR test. PCRs are not 100%, far from it, but are the best worst test option, and less likely to return false results. Therefore it is the better option all round, regardless of what it is testing for. You are correct in that they test for different things, but that does not mean the accuracy figures are any less problematic. 65% is getting close to 50/50 for something that is supposed to be informing whether cities or even regions get tougher or lighter measures imposed. I believe the range is something like 45-67% which is crazy for a mass strategy play. Edited by SW19 CPFC (23 Nov 2020 3.26pm)
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BlueJay UK 23 Nov 20 3.24pm | |
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Originally posted by Rudi Hedman
If the others you’re around are vaccinated then....? If they aren’t then it’s their choice? The vaccines have 90-95% efficacy, don’t they???? Or do they? (I know your anti big pharma) If they do, then certainly. How the roll out goes is a bit of an unknown (since we appear to botch everything up!) but as the vaccines look to be effective, those who would most benefit will hopefully be able to protect themselves imminently.
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SW19 CPFC Addiscombe West 23 Nov 20 3.25pm | |
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Originally posted by Eaglecoops
Is the mRNA the one they have ordered only 5 million doses of or was that the other one? There are several mRNA vaccines in development. Both the Moderna and the Pfizer vaccines use the mRNA approach. Moderna has been ordered by the UK govt to the tune of 5 million doses, Pfizer something like 30m. The Oxford vaccine does not, and helpfully we have 100m doses coming if approved, so this should be the mainstream option for the UK.
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