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Rudi Hedman Caterham 01 Nov 20 8.46pm | |
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Originally posted by BlueJay
Antibodies produced by COVID-19 patients to fight disease have more staying power than once thought - [Link] Quote A new study of 30,000 COVID-19 patients suggests that the antibodies people produce to fight off the virus last longer than previously believed.
The finding should help vaccine makers as well as researchers who have been trying to determine whether COVID-19 survivors can become reinfected. "Some (studies) reported declines in antibodies the first few weeks and first months and that isn't what we have seen," said Ania Wajnberg, lead author of the new study and medical director of Mount Sinai's clinical antibody testing program. "We see a slight decline, but overall a stable level." The paper, published this week in the journal Science, reported that most people with mild to moderate COVID-19 produce antibodies that are still effective five months after the onset of symptoms. Roughly 92% of the patients produce sufficient antibody levels to continue fighting the new coronavirus. Past studies found that antibody levels seemed to drop off faster. The other studies focused on antibodies produced in response to a viral protein known as NP. But it turns out NP may not be a good measure because it has membranes that shield it from the antibodies created by our immune system. The team at Mount Sinai in New York focused instead on the infamous Spike protein, which allows viral cells to attach themselves to human cells. After measuring antibody response in the entire group of 30,000 COVID-19 patients, scientists then followed a smaller subset. This second group consisted of 121 patients, who went on to donate plasma to help others fight COVID-19. When researchers measured antibody levels in the group of 121 they found only a slight drop between three months and five months after symptoms. There was a larger decline at about 148 days, but the antibody levels were still high enough to neutralize the virus. Wajnberg said the Mount Sinai team plans to follow the 121 plasma donors for at least a full year. The study suggests that vaccine makers should target the Spike protein because it spurs a much stronger immune response than the NP protein. A new study in contrast (using a different measure) to the other antibody related study which suggested short term immunity. Here "Roughly 92% of the patients produce sufficient antibody levels to continue fighting the new coronavirus" after 5 months. And that of course is before we get to T Cell immune response. If it turns out that immunity is commonly a year + or more that bodes well for our natural response and possibly the prospects and design of vaccines. Yeah I’ve been saying this. You probably tried being supercilious on this ad well.
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Eaglecoops CR3 01 Nov 20 8.47pm | |
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This paragraph was released by SAGE who also want the schools left open. Read the paragraph carefully and hypothesise why more 20-40 year old females are being admitted with Covid “ He also warned that the virus was "running riot" across all age groups, with up to four times more women aged between 20 and 40 being admitted to hospital with Covid-19 than men in the same age bracket.” It couldn’t perhaps be that children who have been all passing it to each other asymptomatically have passed it onto mums who then spend time nattering to other mums at schools across the country? This sounds a perfectly feasible reason to me for it to have been passed around that age group but patently not obvious to those who want schools to stay open. So let’s lockdown the money generating portion of the population and let the little muck spreaders carry on passing it about, bless ‘em.
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Rudi Hedman Caterham 01 Nov 20 8.49pm | |
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Good spot EC
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Sir James Hird Mount Martha 01 Nov 20 9.05pm | |
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Just to give you info from someone on the ground as it were. There is a big difference in the way countries gather their data, and how they manipulate that into statistics. Clearly the track-and-trace stystem in the UK needs to be made fit for purpose, as it clearly seems to be having minimal effect. Chris Whitty needs an enema, cos he is so full of 5hlt. The "We just have to make up measures as we go along" line was so disheartening from a Professor. Any measures previously introduced have been done too late, resulting in loads of deaths. Now the rate of infections is increasing and deaths are only at a plateau at the moment because all the really old and sick people are dead already. At least wetherspoons are selling Real Ale up until lockdown for only 99p a pint. It's nice to know someone is learning how to cope better with the disease.
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Tim Gypsy Hill '64 Stoke sub normal 01 Nov 20 9.21pm | |
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Originally posted by Eaglecoops
This paragraph was released by SAGE who also want the schools left open. Read the paragraph carefully and hypothesise why more 20-40 year old females are being admitted with Covid “ He also warned that the virus was "running riot" across all age groups, with up to four times more women aged between 20 and 40 being admitted to hospital with Covid-19 than men in the same age bracket.” It couldn’t perhaps be that children who have been all passing it to each other asymptomatically have passed it onto mums who then spend time nattering to other mums at schools across the country? This sounds a perfectly feasible reason to me for it to have been passed around that age group but patently not obvious to those who want schools to stay open. So let’s lockdown the money generating portion of the population and let the little muck spreaders carry on passing it about, bless ‘em. Sage definition n. One venerated for experience, judgment, and wisdom. adj. Having or exhibiting wisdom and calm judgment. adj. Proceeding from or marked by wisdom and calm judgment. Misnomer in my opinion. Mostly SAGE consist of mathematicians. When what we need is scientists, and preferably virologists. Maths is pure logic. Not experience, judgment, and wisdom. But they advise our government at the moment, and the general public believe what they say. So we will be locked down. And if SAGE think that the R number has not fallen 'enough' by 2nd of December, kiss goodbye to Christmas. Quite what 'enough' amounts to is anyones guess. And who gets to decide anyway? So many questions.
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cryrst The garden of England 01 Nov 20 9.25pm | |
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Originally posted by Eaglecoops
This paragraph was released by SAGE who also want the schools left open. Read the paragraph carefully and hypothesise why more 20-40 year old females are being admitted with Covid “ He also warned that the virus was "running riot" across all age groups, with up to four times more women aged between 20 and 40 being admitted to hospital with Covid-19 than men in the same age bracket.” It couldn’t perhaps be that children who have been all passing it to each other asymptomatically have passed it onto mums who then spend time nattering to other mums at schools across the country? This sounds a perfectly feasible reason to me for it to have been passed around that age group but patently not obvious to those who want schools to stay open. So let’s lockdown the money generating portion of the population and let the little muck spreaders carry on passing it about, bless ‘em. Alternatively C19 has taken the older ones who were weak and to survive needs new hosts. Maybe this age in females is perfect for it. Still they must have underlying health issues so was due to die anyway.
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Tim Gypsy Hill '64 Stoke sub normal 01 Nov 20 9.56pm | |
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Coming to a cinema near you. Completely unbelievable? Maybe, maybe not......
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Wisbech Eagle Truro Cornwall 01 Nov 20 10.03pm | |
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Away from the arguments about the best collective response to this crisis, I saw something interesting on TV this evening which encouraged me to look deeper. It seems that people with low levels of Vitamin D stand a 50% higher chance of catching a cold than those with adequate levels. Colds are coronaviruses. They are worse in winter when our Vitamin D levels are lower, due to decreased sunlight and less time outdoors. My own empirical experience suggests that people in the tropics suffer with colds less than us. So I did some Googling and there is quite a lot which supports the hypothesis that low levels of Vitamin D may contribute to the surge in Covid 19. Do some yourself. You could start here:- [Link] I will be buying Vitamin D supplement tomorrow. I have up to this moment always regarded supplements as a waste of money if you ate a balanced diet.
For the avoidance of doubt any comments in response to a previous post are directed to its ideas and not at any, or all, posters personally. |
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cryrst The garden of England 01 Nov 20 10.06pm | |
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Originally posted by Tim Gypsy Hill '64
Coming to a cinema near you. Completely unbelievable? Maybe, maybe not......
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cryrst The garden of England 01 Nov 20 10.08pm | |
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Originally posted by Wisbech Eagle
Away from the arguments about the best collective response to this crisis, I saw something interesting on TV this evening which encouraged me to look deeper. It seems that people with low levels of Vitamin D stand a 50% higher chance of catching a cold than those with adequate levels. Colds are coronaviruses. They are worse in winter when our Vitamin D levels are lower, due to decreased sunlight and less time outdoors. My own empirical experience suggests that people in the tropics suffer with colds less than us. So I did some Googling and there is quite a lot which supports the hypothesis that low levels of Vitamin D may contribute to the surge in Covid 19. Do some yourself. You could start here:- [Link] I will be buying Vitamin D supplement tomorrow. I have up to this moment always regarded supplements as a waste of money if you ate a balanced diet. I have prescribed vit D due to my RA.
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Tim Gypsy Hill '64 Stoke sub normal 01 Nov 20 10.16pm | |
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Originally posted by Wisbech Eagle
Away from the arguments about the best collective response to this crisis, I saw something interesting on TV this evening which encouraged me to look deeper. It seems that people with low levels of Vitamin D stand a 50% higher chance of catching a cold than those with adequate levels. Colds are coronaviruses. They are worse in winter when our Vitamin D levels are lower, due to decreased sunlight and less time outdoors. My own empirical experience suggests that people in the tropics suffer with colds less than us. So I did some Googling and there is quite a lot which supports the hypothesis that low levels of Vitamin D may contribute to the surge in Covid 19. Do some yourself. You could start here:- [Link] I will be buying Vitamin D supplement tomorrow. I have up to this moment always regarded supplements as a waste of money if you ate a balanced diet. If you had a two week holiday in a sunny country, or even if you work outside in this one, you will have enough vit D. The darker your skin is, the less vit D you absorb from the sun. But being outdoors increases it regardless. Colds increase because of not being outside, and affects people who work in factories, offices, etc more than outdoor workers. This has been discussed with regard to 'BAME' people being moe perceptible. Do try to keep up.
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Tim Gypsy Hill '64 Stoke sub normal 01 Nov 20 10.18pm | |
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Originally posted by cryrst
I'm not allowed to go, it's released after lockdown, so they will have to watch it without me.
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